Cardiac Toxicity in Pesticide Formulators exposed to Organo-phosphate Insecticides

  A number of studies indicate ECG and necropsy changes in cardiovascular system in persons accidentally or intentionally (suicidal) exposed to organophosphate group of insecticides. However, there are no reports on CVS changes in people chronically exposed to the insecticides. Studies carried out on pesticide formulators chronically exposed to organophosphate pesticides showed abnormalities of heart rate and ECG abnormalities like tall R wave, prolonged period of conduction (AV block or wide QRS complex) and ventricular premature beats. This is the first report of ECG abnormalities in occupationally exposed subjects.


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